PRODUCT INTRODUCTION

Leucoginase Injection is used in the treatment of some kinds of cancer of white blood cells (leukemia). It may also be used to treat other types of cancer as determined by your doctor. It may be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.

Leucoginase Injection is given as an injection by the doctor, but try to have it the same time each day to make sure it has the best effect. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effect of this medicine includes breathlessness, rash, vomiting, angioedema (swelling of deeper layers of skin), and nausea. It might cause increased blood sugar levels, hence regular blood tests are required to monitor your blood sugar levels, response to the therapy, and any side effects. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

This medicine may lower your body's resistance and increase susceptibility to infections. Infections can sometimes be life-threatening. It is important to use effective contraception to avoid getting pregnant or fathering a child during treatment. Before taking this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

USES OF LEUCOGINASE INJECTION

Blood cancer (Acute lymphocytic leukemia)

BENEFITS OF LEUCOGINASE INJECTION

In Blood cancer (Acute lymphocytic leukemia)

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Leucoginase Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

SIDE EFFECTS OF LEUCOGINASE INJECTION

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Leucoginase

Breathlessness
Rash
Vomiting
Angioedema (swelling of deeper layers of skin)
Edema (swelling)
Nausea
Fatigue
Increased liver enzymes
Diarrhea
Decreased blood pressure
Flushing (sense of warmth in the face, ears, neck and trunk)
Low albumin level in blood
Increased glucose level in blood
Hives

HOW TO USE LEUCOGINASE INJECTION

Your doctor or nurse will give you this medicine. Kindly do not self administer.

HOW LEUCOGINASE INJECTION WORKS

Asparaginase belongs to class of medications called antineoplastic agents. Asparaginase is an enzyme that interferes with natural processes necessary for cancer cell growth, thereby killing or stopping the growth of cancer cells.

SAFETY ADVICE

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Leucoginase Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Leucoginase Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Leucoginase Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Leucoginase Injection does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Leucoginase Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Leucoginase Injection may not be needed in these patients. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Leucoginase Injection in patients with liver disease. Please consult your doctor.
However, regular monitoring of liver function tests is advised while you are taking this medicine.