Drug-Drug Interaction: This medicine may have an interaction with antibiotics (clarithromycin, rifampin, erythromycin), anti-HIV drug (indinavir, nelfinavir, ritonavir), antifungals (itraconazole, ketoconazole) and antidepressant (nefazodone). Besides this, Cleargel Nico Gel 20 gm should not be given with muscle relaxants like atracurium, cisatracurium, doxacurium, metocurine, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium, succinylcholine, tubocurarine and vecuronium.
Drug-Food Interaction: Avoid fried food or oil food.
Drug-Disease Interaction: You should not use Cleargel Nico Gel 20 gm if you have ulcerative colitis, enteritis (inflammation of intestines) or severe diarrhoea caused by antibiotic medicine. People with colitis should avoid using Cleargel Nico Gel 20 gm as it may cause severe, persistent diarrhoea and severe abdominal cramps with the passage of blood in stool or mucus.